Cyclodextrins and their uses a review pdf

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cyclodextrins and their uses a review pdf

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Pharmaceutical applications of cyclodextrins and their derivatives

The design and construction of polymer structures play important roles in the field of polymer science. In addition, polymers can provide good ideas and opportunities for the development of multifunctional materials. Due to the special structure of CDs, it is possible to generate polymers with different structures and functions via chemical reactions. This review describes the classification of CD polymers as well as summarizes the applications of these polymers in environmental, food, and pharmaceutical industries. Finally, the challenges that the CD polymers may face in the future have been proposed. If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using Copyright Clearance Center. Go to our Instructions for using Copyright Clearance Center page for details.

Cyclodextrins and their uses: a review

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Cyclodextrins are a family of cyclic oligosaccharides composed of α-(1,4) linked glucopyranose subunits. Cyclodextrins are useful molecular chelating agents.


Cyclodextrins and Iatrogenic Hearing Loss: New Drugs with Significant Risk

Cellular Mechanisms of Ototoxicity View all 23 Articles. Cyclodextrins are a family of cyclic oligosaccharides with widespread usage in medicine, industry and basic sciences owing to their ability to solubilize and stabilize guest compounds. In medicine, cyclodextrins primarily act as a complexing vehicle and consequently serve as powerful drug delivery agents. Recently, uncomplexed cyclodextrins have emerged as potent therapeutic compounds in their own right, based on their ability to sequester and mobilize cellular lipids. Evidence in mice supports a rapid onset of hearing loss that is dose-dependent.

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Cyclodextrins CDs are abundantly explored in the field of medicines for the design of various types of drug delivery systems. These molecules have a unique structural feature and categorized into hydrophobic, hydrophilic and ionic derivatives.

Pharmaceutical applications of cyclodextrins and their derivatives

Most of the cytotoxic chemotherapeutic agents have poor aqueous solubility. These molecules are associated with poor physicochemical and biopharmaceutical properties, which makes the formulation difficult. An important approach in this regard is the use of combination of cyclodextrin and nanotechnology in delivery system.

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  • Cyclodextrins are a family of cyclic oligosaccharides composed of α-(1,4) linked glucopyranose subunits. Cyclodextrins are useful molecular. Modesto A. - 25.03.2021 at 21:10
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